Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.

GSE64919

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Gene 1.1 ST Array (mogene11st)

Submitter Supplied Information

Description

The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor.

PubMed ID

25893288

Publication Title

The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation.

Total Samples

Submitter’s Institution

European Institute of Oncology

Authors

de Laurentiis A, Hiscott J, Alcalay M

Source Repository

Gene Expression Omnibus (GEO)

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