siRNA induced silencing of CITED1 in HT144 human melanoma cells

GSE66113

Homo sapiens

12 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

To investigate the function of CITED1 in melanoma, its expression was transiently down regulated using CITED1-targeting siRNA. The HT144 melanoma cell line was chosen as it had a relatively high level of detectable CITED1 mRNA and protein expression.

PubMed ID

25755924

Publication Title

Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours.

Total Samples

Submitter’s Institution

Lund University Cancer Center/ Medicon Village

Authors

Howlin J, Cirenajwis H, Lettiero B, Staaf J, Lauss M, Saal L, Borg Å, Gruvberger-Saal S, Jönsson G

Source Repository

Gene Expression Omnibus (GEO)

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