Effects of Diras2-knockdown in murine hippocampal primary cells

Attention-deficit / hyperactivity disorder (ADHD) is a clinically heterogeneous childhood behavioral neurodevelopmental disorder which is highly persistent into adulthood and shows an heritability up to 80%. In previous studies, our group delineated the 9q22 region by both linkage studies and genome-wide association studies as a candidate locus for ADHD. This region harbors the DIRAS2 (MIM: 607863) gene which is coding for a Ras GTPase.

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