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Accession IconGSE68546

Targets of Pax3 and Zic1 in neural crest and cranial placode progenitors

Organism Icon Xenopus laevis
Sample Icon 20 Downloadable Samples
Technology Badge Icon Affymetrix Xenopus laevis Genome 2.0 Array (xlaevis2)

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Description
The transcription factors Pax3 and Zic1 are among the earliest genes activated at the neural plate border. Pax3 and Zic1 in combination promote neural crest fate, while Zic1 alone regulate cranial placode progenitor formation. We used microarrays to identify the global repertoire of genes activated by these facors individually or in combination to gain insights into the molecular mechanisms underlying cell fate decision at the neural plate border.
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