Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I)

In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for target evaluation purposes during early drug discovery

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Verbist B, Klambauer G, Vervoort L, Talloen W, QSTAR Consortium., Shkedy Z, Thas O, Bender A, Göhlmann HW, Hochreiter S