5-aza treatment of breast cancer and non-tumorigenic breast cells

GSE71363

Homo sapiens

17 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

CpG hypermethylation in gene promoters is a frequent mechanism of tumor suppressor gene silencing in various types of cancers. 5-aza-2'-deoxycytidine (AZA) is a DNA demethylating and anti-cancer agent resulting in induction of genes suppressed via DNA hypermethylation.

PubMed ID

26421063

Publication Title

Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer.

Total Samples

Submitter’s Institution

Bilkent University

Authors

Sayar N, Karahan G, Konu O, Bozkurt B, Bozdogan O, Yulug IG

Source Repository

Gene Expression Omnibus (GEO)

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