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Accession IconGSE71404

Expression array analysis of the hepatocyte growth factor (HGF) invasive program

Organism Icon Homo sapiens
Sample Icon 33 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

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Description
HGF stimulates mitogenesis, motogenesis and morphogenesis in most epithelial target cells. Selective inhibition of HGF signaling blocks spontaneous metastasis, but not primary tumor growth, in the prostate adenocarcinoma derived PC3M cell xenograft model.
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36
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