Microarray expression profiling of discrete microdissected mouse inner ear tissues from E9 to E15 at half-day intervals.

The inner ear in mammals is derived from a simple ectodermal thickening called the otic placode. Through a series of complex morphological changes, the placode forms the mature inner ear comprising of the auditory organ (cochlea) and the vestibular/balance organs (utricle, saccule, and three semi-circular canals). The vast majority of genes known to be involved during inner ear development have been found through mutational screens or by chance.

64

Sajan SA, Warchol ME, Lovett M