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Accession IconGSE75620

Transcriptomic study of hepatocarcinoma cells exposed to sorafenib

Organism Icon Homo sapiens
Sample Icon 9 Downloadable Samples
Technology Badge Icon Affymetrix Human Gene 2.1 ST Array (hugene21st)

Submitter Supplied Information

Description
sorafenib is the treatment of reference for hepatocellular carcinoma (HCC). We applied sorafenib on the human HCC cell line Huh7 and the subclone shRb, carrying a stable knock-down of the expression of the RB1 gene, a key regulator of liver carcinogenesis. Our aim was to better understand the physiologic and metabolic consequences of the exposure of HCC cells to sorafenib.
PubMed ID
Total Samples
10

Samples

Show of 10 Total Samples
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Title
Specimen part
Cell line
Treatment
Processing Information
Additional Metadata
Huh+S#6
hepatocarcinoma cells
huh7
sorafenib
Sh+S#12
hepatocarcinoma cells
shrb
sorafenib
Huh#1
hepatocarcinoma cells
huh7
none
Sh#9
hepatocarcinoma cells
shrb
none
Sh+S#10
hepatocarcinoma cells
shrb
sorafenib
Sh+S#11
hepatocarcinoma cells
shrb
sorafenib
Sh#7
hepatocarcinoma cells
shrb
none
Sh#8
hepatocarcinoma cells
shrb
none
Huh#3
hepatocarcinoma cells
huh7
none
Sample not processed
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Huh+S#5
hepatocarcinoma cells
huh7
sorafenib
NA
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