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GSE77475
Human neural stem cells transduced with oncogenic elements associated with aggressive medulloblastoma
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Homo sapiens
6 Downloadable Samples
Affymetrix HT HG-U133+ PM Array Plate (hthgu133pluspm)
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Description
Human neural stem and progenitor cells transformed with c-MYC, dominant-negative p53, constitutively active AKT and hTERT formed tumors in mice that recapitulated Group 3 medulloblastoma in terms of pathology and expression profile
PubMed ID
27012813
Publication Title
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.
Total Samples
6
Submitter’s Institution
UCSD
Authors
Hanaford AR
,
Archer TC
,
Price A
,
Kahlert UD
,
Maciaczyk J
,
Nikkhah G
,
Kim JW
,
Ehrenberger T
,
Clemons PA
,
Dančík V
,
Seashore-Ludlow B
,
Viswanathan V
,
Stewart ML
,
Rees MG
,
Shamji A
,
Schreiber S
,
Fraenkel E
,
Pomeroy SL
,
Mesirov JP
,
Tamayo P
,
Eberhart CG
,
Raabe EH
Source Repository
Gene Expression Omnibus (GEO)
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