Transcriptional changes in Lhx8 Null newborn mouse ovaries

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GSE7774

Mus musculus

5 Downloadable Samples

Affymetrix Mouse Expression 430A Array (moe430a)

Submitter Supplied Information

Description

Lhx8 is a homeobox gene expressed in oocytes and critical in oogenesis. Lhx8 deficiency leads to rapid loss of postnatal oocytes. Early oocyte differentiation is poorly understood. We hypothesized that lack of Lhx8 perturbs global expression of genes preferentially expressed in oocytes. We compared Lhx8 knockout and wild type ovaries using Affymetrix 430 2.0 microarray platform.

PubMed ID

18509161

Publication Title

Lim homeobox gene, lhx8, is essential for mouse oocyte differentiation and survival.

Total Samples

Submitter’s Institution

Baylor College of Medicine

Authors

Choi Y, Ballow DJ, Xin Y, Rajkovic A

Source Repository

Gene Expression Omnibus (GEO)

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