Expression data from IMQ-induced psoriasis-like skin inflammation in miR-146a-/- and C57BL6J mice

GSE78057

Mus musculus

16 Downloadable Samples

Affymetrix Mouse Gene 2.1 ST Array (mogene21st)

Submitter Supplied Information

Description

miR-146a acts as a negative feedback regulator of inflammation. To investigate the role of miR-146a in psoriasis psoriasiform skin inflammation was indeuced in Mir-146a-/- and wild type mice (C57BL6J) by topical applciation of imiquimod (IMQ)-cream (Aldara).

PubMed ID

27568078

Publication Title

MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis.

Total Samples

Submitter’s Institution

Karolinska Institutet

Authors

Srivastava A, Nikamo P, Lohcharoenkal W, Li D, Meisgen F, Xu Landén N, Ståhle M, Pivarcsi A, Sonkoly E

Source Repository

Gene Expression Omnibus (GEO)

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