Effect of JAK blockade on IFNa response in B cells in vitro
Mus musculus
32 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)
Submitter Supplied Information
Description
B cells respond robustly to type 1 interferons which signal through JAK1 and TYK2. Here we analyzed the effects of a panel of JAK inhibitors on the IFNa transcriptional response in activated B cells in vitro.