Expression data from mouse white adipose tissue lacking CNOT3, a core subunit of the CCR4-NOT complex

mRNA degradation critically contributes to tissue development and function as well as transcription. The CCR4-NOT complex serves as a major deadenylase that initiates mRNA degradation.

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Li X, Morita M, Kikuguchi C, Takahashi A, Suzuki T, Yamamoto T