Identification of potential ABBV-075 responsive markers in mouse whole blood

GSE89935

Mus musculus

15 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

To identify genes that are modulated by BET inhibitors in blood, we determined global gene expression changes in ABBV-075-treated mouse whole blood samples

PubMed ID

27903752

Publication Title

HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues.

Total Samples

Submitter’s Institution

Abbvie

Authors

Lin X, Huang X, Uziel T, Hessler P, Albert DH, Roberts-Rapp LA, McDaniel KF, Kati WM, Shen Y

Source Repository

Gene Expression Omnibus (GEO)

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