A model of exposure to extreme environmental heat uncovers the human transcriptome to heat stress

The molecular mechanisms by which individuals subjected to environmental heat stress either adapt or develop heat-related complications are not well understood. We analysed the changes in blood mononuclear gene expression patterns in human volunteers exposed to an extreme heat in a sauna (temperature of 78 6 C).

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Bouchama A, Aziz MA, Mahri SA, Gabere MN, Dlamy MA, Mohammad S, Abbad MA, Hussein M