Transcriptome analysis of human T-cell Jurkat cell line in resting cells (t0) and at 8h, 24h and 48h post-activation using Raji B-cells conjugated with superantigen (SEE)

GSE94970

Homo sapiens

12 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

Activation of T-cells induces dramatic changes in genome organisation and gene transcription. Here we identify changes in transcriptional profiles at 8h, 24h and 48 post activation

PubMed ID

28424353

Publication Title

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments.

Total Samples

Submitter’s Institution

University of Edinburgh

Authors

Robson MI, de Las Heras JI, Czapiewski R, Sivakumar A, Kerr ARW, Schirmer EC

Source Repository

Gene Expression Omnibus (GEO)

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