Microarray analysis of the impact of ParB excess on gene expression in Pseudomonas aeruginosa

GSE95647

Pseudomonas aeruginosa

11 Downloadable Samples

Affymetrix Pseudomonas aeruginosa Array (paeg1a)

Submitter Supplied Information

Description

In Pseudomonas aeruginosa, partitioning protein ParB facilitates segregation of newly replicated chromosomes but is not essential for cell survival. Unlike in other bacteria, inactivation of parB leads to major changes of the transcriptome, suggesting that, directly or indirectly, ParB plays a role in regulation of gene expression in this organism.

PubMed ID

28732084

Publication Title

Increased ParB level affects expression of stress response, adaptation and virulence operons and potentiates repression of promoters adjacent to the high affinity binding sites parS3 and parS4 in Pseudomonas aeruginosa.

Total Samples

Submitter’s Institution

Institute of Biochemistry and Biophysics, PAS

Authors

Kawalek A, Glabski K, Bartosik AA, Fogtman A, Jagura-Burdzy G

Source Repository

Gene Expression Omnibus (GEO)

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