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Accession IconGSE9650

Chronic viral infection of naive, effector, memory and exhausted virus-specific CD8 T cells

Organism Icon Mus musculus
Sample Icon 25 Downloadable Samples
Technology Badge Icon Affymetrix Murine Genome U74A Array (mgu74a), Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

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Description
CD8 T cells normally differentiate from resting nave T cells into function effector and then memory CD8 T cells following acute infections. During chronic viral infections, however, virus-specific CD8 T cells often become exhausted. We used microarrays to examine the gene expression differences between naive, effector, memory and exhausted virus-specific CD8 T cells following lymphocytic choriomeningitis virus infection.
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