Gene expression data in aortic tissue from rats with experimental preeclampsia, healthy pregnancy and non pregnant rats

Normal pregnancy requires adaptations of the maternal vasculature. During preeclampsia these adjustments are not well established, resulting in maternal hypertension and proteinuria. The effects of preeclampsia on the maternal vasculature are not yet fully understood. We aimed to identify gene expression differences in the aorta between non pregnant, healthy pregnant, and experimental preeclamptic rats using a genome wide approach.

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Lip SV, van der Graaf AM, Wiegman MJ, Scherjon SA, Boekschoten MV, Plösch T, Faas MM