Expression data from IMR90 cells expressing either E7-ca-STAT5A-shNTC vs E7-ca-STAT5a-shSOCS1 at 7 days post infection

GSE98216

Homo sapiens

3 Downloadable Samples

Affymetrix Human Gene 2.0 ST Array (hugene20st)

Submitter Supplied Information

Description

SOCS1 plays a role in cellular senescence. Knocking down SOCS1 in senescence induced by the STAT5 oncogene results in senescence bypass by preventing p53 activation

PubMed ID

29081404

Publication Title

SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes.

Total Samples

Submitter’s Institution

Universit de Montral

Authors

Saint-Germain E, Mignacca L, Vernier M, Bobbala D, Ilangumaran S, Ferbeyre G

Source Repository

Gene Expression Omnibus (GEO)

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