PTBP1 excludes UPF1 to protect long 3''UTRs from nonsense-mediated mRNA decay

SRP045065

Homo sapiens

8 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

RNA-seq analysis of human 293 Tet-off cells depleted of PTBP1 and UPF1 alone and in tandem with specific siRNAs. Overall design: siRNA-based depletion of PTBP1, UPF1, and PTBP1/UPF1 together, with a validated non-silencing siRNA as a control.

PubMed ID

26744779

Publication Title

Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway.

Total Samples

Submitter’s Institution

No associated institution

Authors

Ge Z, Quek BL, Beemon KL, Hogg JR

Source Repository

Sequence Read Archive (SRA)

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