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Accession IconSRP117763

Association of distinct gut microbiome patterns with consensus molecular subtypes of colorectal cancer

Organism Icon Homo sapiens
Sample Icon 3 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
For the study, colorectal cancer tumour samples were collected from 34 patients and transcriptome sequencing of the samples was done to classify them into consensus molecular subtypes of colorectal cancer. To quantify relative abundances of bacterial strains in the samples, 16S rRNA amplicon metabarcoding was done and the non-human part of the transcriptome data was also analysed. Analysis of the association between the subtypes and microbiome was carried on and the targeted quantitative PCR was done to confirm the findings.
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