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Accession IconSRP132271

Differential gene expression in the stellate ganglia of 16 week wistar and spontaneously hypertensive rat samples

Organism Icon Rattus norvegicus
Sample Icon 16 Downloadable Samples
Technology Badge IconIllumina HiSeq 4000

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Description
Hypertension remains a poorly understood condition, and the understanding of the sympathetic nervous systems role in this disease remains even more limited. In this study, RNA-sequencing is used to identify transcriptomal differences in the sympathetic stellate ganglia between the 16-week-old normotensive wistar strain and the spontaneously hypertensive rat strain.This dataset should allow for further molecular characterisation of hypertensive changes in a cardiac-innervating sympathetic ganglion. Overall design: Comparison of normotensive and hypertensive rat stellate ganglia. 4 biological replicates for both 16 week wistar and SHR stellate ganglia samples were contrasted
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16
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