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Accession IconSRP139759

A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation

Organism Icon Homo sapiens
Sample Icon 15 Downloadable Samples
Technology Badge IconNextSeq 500

Submitter Supplied Information

Description
Use NGS-transcriptome profiling (RNA-seq) to investigate deregulated genes involved in the proliferative effects of ID-8 and Harmine after hypoxia-induced damage in primary human proximal tubular epithelial cells (HPTECs) Overall design: Examination of differentially expressed genes in HPTECs treated with 1uM of ID-8; or 1uM of Harmine; or EGF in comparison to cells without treatment after 24 hours of hypoxia, in triplicates
PubMed ID
Total Samples
15
Submitter’s Institution
No associated institution

Samples

Show of 15 Total Samples
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Accession Code
Title
Specimen part
Subject
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Additional Metadata
EGF free_rep2
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
ID-8_rep1
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
EGF free_rep1
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
Harmine_rep2
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
ID-8_rep3
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
Hypoxia_rep3
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
Harmine_rep1
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
Hypoxia_rep2
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
Hypoxia_rep1
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
ID-8_rep2
proximal tubular epithelial cells
human proximal tubular epithelial cells
NA
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