RNA sequencing of SRSF3 depleted pluripotent cells

SRP143519

Mus musculus

4 Downloadable Samples

NextSeq 550

Submitter Supplied Information

Description

RNA seqeuncing was performed to identifiy changes in genes expression and alternative splicing following SRSF3 depletion in pluripotent stem cells. Overall design: Induced pluripotent stem cells (iPSCs) generated from reprogrammable conditional SRSF3 knockout (SRSF3-KO/OKSM) mouse embryonic fibroblasts (MEFs) were induced for 24h to deplete SRSF3 and RNA seqeuncing was performed.

PubMed ID

29741478

Publication Title

SRSF3 promotes pluripotency through <i>Nanog</i> mRNA export and coordination of the pluripotency gene expression program.

Total Samples

Submitter’s Institution

No associated institution

Authors

Ratnadiwakara M, Archer SK, Dent CI, Ruiz De Los Mozos I, Beilharz TH, Knaupp AS, Nefzger CM, Polo JM, Anko ML

Source Repository

Sequence Read Archive (SRA)

No rows found