A comprehensive examination of the molecular and pathological changes of the colonic injury response

Gene expression changes in the murine colon were determined at early and late stages following colonoscopic-guided pinch biopsy by comparing normal mucosa of sham treated mice to wound beds Overall design: RNA seq analysis was carried out on colonic mucosa of mice 1 hour, 6 hours, 3 days or 6 days in normal tissue following sham treatment or the wound bed following pinch biopsy

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Montrose DC, Zhou XK, McNally EM, Sue E, Wang H, Nishiguchi R, Verma A, Elemento O, Simpson KW, Yang P, Hla T, Dannenberg AJ