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Accession IconSRP158468

Adipose tissue RNAseq in T-cell-specific IFNAR-deficient mice.

Organism Icon Mus musculus
Sample Icon 12 Downloadable Samples
Technology Badge IconIllumina HiSeq 4000

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Description
We sequenced whole adipose tissue from control and LCMV infected mice 6dpi, in control vs T cell-specific IFNAR knockoutmice to understand the transcriptional changes in adipose tissue upon loss of type I IFN-T cell singaling axis, and how it contributes to cachexia. Overall design: inguinal fat pad (after removing iLN) was used for sequencing in control and infected mice (LCMV clone13 2x10^6PFU), this was done in two genotypes (IFNARfl/fl) as controls, vs (IFNARfl/fl-CD4cre/+) as T-cell specific IFNAR knockouts.
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12
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No associated institution

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