RNA-seq of WT, Tet1-/-, Tet2-/-, Tet1-/-:Tet2-/- (DKO), and Tet1-/-:Tet2-/-:Tet3-/- (TKO) murine embryonic stem cells following six days of LIF withdrawal.

SRP159908

Mus musculus

24 Downloadable Samples

NextSeq 500

Submitter Supplied Information

Description

The goal of this study was to identify transcriptional differences between varying combinations of Tet deletion clones following six days of LIF withdrawal. These libraries were generated from cells under normal culture conditions. Overall design: RNA-seq libraries were generated for 3 WT, 3 Tet1-/-, 2 Tet2-/-, DKO, and TKO clones. Sequencing was done on a Illumina NextSeq 500 for all paired end reads

PubMed ID

31286885

Publication Title

Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression.

Total Samples

Submitter’s Institution

No associated institution

Authors

Reimer M Jr, Pulakanti K, Shi L, Abel A, Liang M, Malarkannan S, Rao S

Source Repository

Sequence Read Archive (SRA)

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