8-OxoG in GC-rich Sp1 binding sites enhances gene transcription during adipose tissue development in juvenile mice [RNA-Seq]

We observed that transcriptional activity and the number of active genes were significantly correlated with the distribution of 8-oxoG in gene promoter regions, as determined by liquid chromatography/mass spectrometry (LC/MS), and 8-oxoG and RNA sequencing Overall design: RNA-sequencing of lung and adipose tissues isolated from two juvenile female C57BL/6 mice

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Park JW, Han YI, Kim SW, Kim TM, Yeom SC, Kang J, Park J