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Accession IconSRP212738

The Toll signaling pathway targets the insulin-like peptide Dilp6 to inhibit growth in Drosophila

Organism Icon Drosophila melanogaster
Sample Icon 64 Downloadable Samples
Technology Badge IconIllumina HiSeq 4000

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Description
To identify genes that mediate altered communication between fat body and peripheral tissues, we report the gene expression changes in Drosophila third instar larval fat bodies with or without constitutively-active Toll (Toll10b) to activate innate immune signaling, myristoylated Akt (myrAkt) to activate insulin signaling, or both transgenes to bypass the block from Toll signaling to the upstream part of the insulin signaling pathway Overall design: Comparison of RFP/GFP (Control), Toll10b/GFP (Toll10b), RFP/myrAkt (myrAkt), and Toll10b/myrAkt (Toll10b + myrAkt)
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64
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