Description

To dissect the functions of syndecan-1 in the nucleus, and separate them from functions related to the cell-surface, we transfected fibrosarcoma cells with two constructs: one encoding the full-length syndecan-1, which translocates to the nucleus and another encoding syndecan-1 lacking the RMKKK nuclear localization signal with hampered nuclear translocation.

Publication Title

Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1.

Sample Metadata Fields

Specimen part, Cell line