Schizophrenia is associated with alterations in working memory that reflect dysfunction of dorsolateral prefrontal cortex (DLPFC) circuitry. Working memory depends on the activity of excitatory pyramidal cells in DLPFC layer 3, and to a lesser extent in layer 5.
Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.
Cell line, Time
View SamplesToxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.
Cell line, Time
View SamplesToxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.
Cell line, Time
View SamplesInfection of RAW264.7 cells with RHku80 parasites or mock-infection for 24 hours
Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates.
Cell line
View SamplesToxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.
Cell line, Time
View SamplesComparison of Total RNA and Polysome-bound RNA populations in deltaTOR containing cells and control cells upon hepatocyitc differentiation.
Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
Specimen part, Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Control of daily transcript oscillations in Drosophila by light and the circadian clock.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Integration of light and temperature in the regulation of circadian gene expression in Drosophila.
No sample metadata fields
View SamplesInfection of RAW264.7 cells for 24 hours with 32 Toxoplasma Progeny from a Type II x Type III cross
GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response.
No sample metadata fields
View Samples