refine.bio
  • Search
      • Normalized Compendia
      • RNA-seq Sample Compendia
  • Docs
  • About
  • My Dataset
github link
Showing
of 245 results
Sort by

Filters

Technology

Platform

accession-icon GSE66332
Gene expression profiling of perinatal or adult regulatory T cells (Tregs)
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

A comparative analysis of gene expression of 3 different experiments; 1. Perinate or adult-tagged GFP+YFP+ and bulk GFP+YFP- Tregs, 2. FL or BM-derived Tregs 3. Perinate or adult thymic Tregs.

Publication Title

Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE66402
Gene expression profiling of perinatal or adult medullary thymic epithelial cells (MECs)
  • organism-icon Mus musculus
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

A comparative analysis of gene expression of perinate or adult Aire-GFP+ and GFP- MECs in WT or Aire-KO thymus

Publication Title

Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE141118
shRNA screen of factors involved in Aire-sensitive gene expression on their 3'UTR lengthening
  • organism-icon Homo sapiens
  • sample-icon 27 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

CLP1 controls the expression of Aire-sensitive genes with proximal pAs and their shortening in HEK293 cells

Publication Title

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.

Sample Metadata Fields

Cell line

View Samples
accession-icon GSE21900
Expression profiling of the Otx2 CKO retina
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

In the vertebrate retina, the Otx2 transcription factor plays a crucial role in the cell fate determination of both rod and cone photoreceptors. Otx2 conditional knockout (CKO) mice exhibited a total absence of rods and cones in the retina due to their cell fate conversion to amacrine-like cells. In order to investigate the entire transcriptome regulated by Otx2 in the developing retina, we performed microarray analysis on the Otx2 CKO retina.

Publication Title

Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.

Sample Metadata Fields

Specimen part, Time

View Samples
accession-icon SRP092208
Effect of Aire deficiency on peripheral Tgd17 gene expression
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

We examine the transcriptional profile of lung Tgd17 cells from mice that are deficient for Aire compared to wild-type mice. Overall design: Duplicate samples of 500 sorted lung resident CD27- Vg1,2,4,5- gd T cells from

Publication Title

Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.

Sample Metadata Fields

Sex, Age, Specimen part, Cell line, Subject

View Samples
accession-icon GSE52686
Expression data from mDCT cell-line over-expressing hMR
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Target gene of mineralocorticoid receptor (MR) is comparatively unknown, although distal convoluted tubule (DCT) expresses MR in in vivo.

Publication Title

Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor.

Sample Metadata Fields

Cell line, Treatment

View Samples
accession-icon GSE5231
IGF1R Mediates Mammalian Immune Function in Response to FEZL
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5225
Expression data from OCUBM cells trasfected with IGF1R
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To investigate genes that might influence resistance to infection through IGF1R, we screened human breast cancer-derived OCUB-M cells transfected with expression vector encoding IGF1R using microarray analysis.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5224
Expression data from OCUBM cells trasfected with 12G FEZL
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To identify genes that influence resistance to mastitis, we scanned

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE145367
GeneChip Expression Array
  • organism-icon Rattus norvegicus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Gene expression analysis to compare control cells and sorted cells

Publication Title

Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.

Sample Metadata Fields

Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

BSD 3-Clause LicensePrivacyTerms of UseContact