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accession-icon GSE66303
Transcriptional responses to i.v. administered I-131 in various mouse normal tissues underlie diurnal variation
  • organism-icon Mus musculus
  • sample-icon 136 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

Circadian rhythm study on transcriptional responses to i.v. administered 90 kBq iodine-131 after 24h in mouse kidney cortex and medulla, liver, lungs, spleen, and thyroid.

Publication Title

Circadian rhythm influences genome-wide transcriptional responses to (131)I in a tissue-specific manner in mice.

Sample Metadata Fields

Sex, Specimen part, Time

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accession-icon GSE32306
Transcriptional response of mouse thyroids following in vivo 211At exposure reveals distinct gene expression profiles
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

Transcriptomic profiling of normal mouse thyroid tissue following 211At irradiation

Publication Title

Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles.

Sample Metadata Fields

Specimen part

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accession-icon GSE56894
Transcriptional response in normal tissues in mice after 211At administration - dependency of absorbed dose, dose-rate and time
  • organism-icon Mus musculus
  • sample-icon 80 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

RNA microarray analysis of low-dose and dose rate responses versus time after i.v. administration of 211At.

Publication Title

Transcriptional response in normal mouse tissues after i.v. (211)At administration - response related to absorbed dose, dose rate, and time.

Sample Metadata Fields

Sex, Specimen part, Time

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accession-icon GSE97293
Genome-wide multi-omics profiling reveals extensive genetic complexity in 8p11-p12 amplified breast carcinomas
  • organism-icon Homo sapiens
  • sample-icon 53 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE17636
Expression data from breast cancer cells overexpressing NF1-C2
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

NF1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing FoxF1. We used microarray to identify direct targets for NF1-C2.

Publication Title

Nuclear Janus-activated kinase 2/nuclear factor 1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing Forkhead box F1.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE20486
Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma
  • organism-icon Homo sapiens
  • sample-icon 97 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

Genomic and expression profiling using 38K BAC array-CGH and Illumina HT-12 beadchips were performed on 97 diploid invasive breast tumors to assess the impact of gene dosage on gene expression patterns and the effect of other mechanisms on transcriptional levels. Patient stratification was performed according to axillary lymph node status (node-negative, pN0; node-positive, pN1) and overall survival (>8-year survivors; breast cancer-specific mortality within 8 years of diagnosis). Array-CGH results was validated by FISH using tumors showing HER2/neu gene amplification and expression profiling was confirmed using qPCR for 16 transcripts.

Publication Title

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma.

Sample Metadata Fields

Disease, Disease stage

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accession-icon GSE20462
Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma (transcriptomic profiling)
  • organism-icon Homo sapiens
  • sample-icon 97 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

Genomic and expression profiling using 38K BAC array-CGH and Illumina HT-12 beadchips were performed on 97 diploid invasive breast tumors to assess the impact of gene dosage on gene expression patterns and the effect of other mechanisms on transcriptional levels. Patient stratification was performed according to axillary lymph node status (node-negative, pN0; node-positive, pN1) and overall survival (>8-year survivors; breast cancer-specific mortality within 8 years of diagnosis). Array-CGH results was validated by FISH using tumors showing HER2/neu gene amplification and expression profiling was confirmed using qPCR for 16 transcripts.

Publication Title

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma.

Sample Metadata Fields

Disease, Disease stage

View Samples
accession-icon GSE97177
Genome-wide multi-omics profiling reveals extensive genetic complexity in 8p11-p12 amplified breast carcinomas [expression]
  • organism-icon Homo sapiens
  • sample-icon 53 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

Transcriptomic profiling of human breast tumors.

Publication Title

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE80024
Optimization of 177Lu-octreotate treatment of neuroendocrine tumours
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 87 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina MouseRef-8 v2.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Time-dependent transcriptional response of GOT1 human small intestine neuroendocrine tumor after <sup>177</sup>Lu[Lu]-octreotate therapy.

Sample Metadata Fields

Time

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accession-icon SRP111102
Genome-wide multi-omics profiling reveals extensive genetic complexity in 8p11-p12 amplified breast carcinomas [RNA-seq]
  • organism-icon Homo sapiens
  • sample-icon 23 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Transcriptomic profiling of human breast tumors using RNA sequencing Overall design: Evaluation of common fusion transcripts, genetic variants, and gene expression patterns in 8p11-p12 amplified breast carcinomas

Publication Title

Genome-wide multi-omics profiling of the 8p11-p12 amplicon in breast carcinoma.

Sample Metadata Fields

Age, Specimen part, Subject

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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