African American men are disproportionately affected by both vitamin D deficiency and increased risk of prostate cancer.
Prostatic compensation of the vitamin D axis in African American men.
Specimen part
View SamplesPre-LVAD and explanted ischemic and nonischemic cardiomyopathy and nonfailing hearts all normalized with RMA
Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.
Specimen part, Cell line
View SamplesMicroarray studies was performed to analyze gene expression changes in NCI-H2347 cells after treatment with 50 M pioglitazone for 12hr, 24hr and 48hrs.
Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.
Specimen part, Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.
Sex, Specimen part, Disease
View SamplesThis study aimed to generate a new panel of comprehensively, genomically characterized high-grade serous ovarian carcinoma (HGSOC) cell line and xenograft models. Multidimensional genomic data were generated and compared between cell lines/xenografts and the tumours they were derived from, indicating the cell lines/xenografts are highly similar to their patient-matched tumours. Cell line/xenograft data were also compared to TCGA ovarian tumours to show the cell lines are good models of clinical HGSOC.
A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.
Sex, Disease
View SamplesTo monitor global transcript changes after Paf1C depletion we transfected ESCs with esiRNA targeting Ctr9 and control esiRNA (Luc).
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Age, Specimen part, Disease stage, Race
View SamplesThis study identified DNA methylation patterns that were associated with tumor subtypes, disease outcome, and distinct metabolome and gene expression patterns.
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Age, Specimen part, Disease stage, Race
View SamplesCharacterization of gene expression changes upon development of taxane-platin drug resistance in NSCLC cells and further, upon treatment of these resistant cells with the Jumonji KDM inhibitor, GSK-J4. Overall design: Comparison of gene expression changes between H1299 Parental cells (chemo-sensitive) and H1299 T18 cells (taxane-platin resistant), and comparison of H1299 T18: GSK-J4 treated vs. H1299 T18: DMSO control.
Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.
Sex, Age, Treatment, Race, Subject
View Samples