We show that Bmx-deficiency reduces angiotensin II -induced cardiac hypertrophy and pathological gene expression
Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling.
Sex
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VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart.
Sex, Age, Specimen part
View SamplesWe show that an excess of VEGF-B protects the heart via adaptive cardiac hypertrophy and increased coronary arterial reserve, and by inducing a shift from lipid to glucose metabolism.
VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart.
Sex, Age, Specimen part
View SamplesBy analyzing 250 astrocyte single cell transcriptomes from adult brain, we provide gene expresssion profile of brain astrocyte Overall design: We chose adult mice about 3 months old and analysed single cells in the brain. We chose a methodology based on fluorescence-activated cell sorting (FACS) into 384-well plates followed by the SmartSeq2 methodology.
Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types.
Specimen part, Cell line, Subject
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