This study compares cardiac induction time-courses using (i) wild-type hESCs subjected to a standard directed differentiation protocol, (ii) EOMES knockout hESCs subjected to the same protocol, and (iii) EOMES KO / TET-ON hESCs subjected to a TET-ON protocol.
Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES.
Cell line, Time
View SamplesHuman ES cells respond to activation of the BMP and WNT signaling by upregulating target genes. A 4h time-point following signaling factor stimulation was chosen to reveal immediate-early induced genes which are likely to be direct targets.
Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES.
Cell line, Treatment, Time
View Samples