This study goal is to obtain the different expression genes induced by APMAP knockdown.
No associated publication
Sex, Specimen part, Cell line
View SamplesThis study goal is to obtain the different expression genes induced by cholesterol.
No associated publication
Sex, Specimen part, Disease, Cell line
View SamplesExamination of whole genome gene expression profiles from the placentas of cloned (somatic cell nuclear transfer, SCNT) and normally produced (control) calves using RNA-seq.The differentially expressed genes were analyzed between SCNT and control placentas.
No associated publication
Sex
View SamplesLaboratorial research
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Specimen part, Cell line
View Sampleshuman gene Transcriptome analysis
No associated publication
Sex, Age, Specimen part
View Samples593 FFPE colorectal cancer samples were used to generate three prediction models: Recurrence prediction, 5FU efficacy prediction, and FOLFOX efficacy prediction
Building personalized treatment plans for early-stage colorectal cancer patients.
Specimen part
View SamplesThe tissue of origin form metastatic tumors is sometimes difficult to identify from clinical and histologic information. Gene expression signatures are one potential method for identifying the tissue of origin. In the development of algorithms to identify tissue of origin, a collection of human tumor metastatic specimens with known primary sites or primary tumors with poor differentiation are very useful in identifying gene expressions signatures that can classify unknown specimens as to the tissue of origin. Here we describe a series of 276 such tumor specimens used for this purpose. The specimens are poorly differentiated, undifferentiated and metastatic specimens from tumors of the following types/tissues of origin: breast, liver, non-Hodgkin's lymphoma, non-small cell lung cancer, ovary, testicular germ cell, thyroid, kidney, pancreas, colorectal cancer, soft tissue sarcoma, bladder, gastric cancer, prostate and melanoma. This data combined with other series (GSE2109) was used to validate a proprietary tumor classification algorithm of Pathwork Diagnostics. The results of this validation set (N = 545 CEL files) showed that the algorithm correctly identified the tissue of origin for 89.4% of the specimens.
Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin.
Sex, Age
View Samples211 FFPE NSLC surgical samples were used to generate recurrence prediction models
Generating a robust prediction model for stage I lung adenocarcinoma recurrence after surgical resection.
No sample metadata fields
View SamplesTo gain the transcriptome alteration caused by knockdown of PHF8 and USP7 in MCF-7 cells
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No sample metadata fields
View SamplesMTDH was identified to be a functional gene in cancer progression. We overexpressed the gene in MCF7 cells and explored its functions in cancer stem cell maintainance.
No associated publication
Sex, Specimen part, Disease, Cell line
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