Inflorescence apices of hec1,2,3 triple mutants and ethanol induced 35S:AlcR, AlcA:HEC1 plants were copared to wild-type or ethanol induced 35S:AlcR, AlcA:GUS apices, respectively.
A regulatory framework for shoot stem cell control
Specimen part
View SamplesThe aim of the project is to compare effects of Swi1 protein prionization and its deletional inactivation in Saccharomyces cerevisiae on transcriptomic level. All yeast samples were grown on solid MD media with galactose as a sole carbon source.
No associated publication
Specimen part, Disease, Cell line
View SamplesTransgenic GFAP-, NES-, and SYN- CRE mice were injected with a lenti-viral construct containing a floxed RFP directly upstream of a cassette containing si-p53, GFP, and mutant HRAS. Tumors arising from the various CRE tissue specific promoters and differing injections sites were compared to normal hippocampus and cortex.
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
No associated publication
Specimen part
View SamplesWe cultured hESC and hiPSC lines and compared the transcriptome of untreated cells with cells treated with Activin or BMP4 during 5 days
No associated publication
Cell line
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.
Specimen part, Cell line
View SamplesGiven that the NF-B pathway plays an important role in tumor development and that IKK2 is the seminal kinase responsible for NF-B pathway activation, we were particularly interested in exploring the therapeutic potential of IKK2 inhibition in non-small cell lung cancers.
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
Specimen part
View SamplesRecently, 2-aminoxy-3-phenylpropionic acid (L-AOPP) had been demonstrated to possess an inhibitory activity against IAA biosynthesis but the molecular basis of the action was unclear. To investigate the function of L-AOPP in relation to Auxin biosynthesis, we conducted microarray analysis.
No associated publication
Specimen part
View SamplesRecently, 2-aminoxy-3-phenylpropionic acid (L-AOPP) had been demonstrated to possess an inhibitory activity against IAA biosynthesis but the molecular basis of the action was unclear. To investigate the function of L-AOPP, we conducted microarray analysis using the shoot apical meristem (SAM) part of A. thaliana in addition to whole plants after the treatment of L-AOPP.
No associated publication
Specimen part
View SamplesAMPK (AAK-2) and calcineurin (TAX-6) mediate longevity exclusively through post-translational modification of CRTC-1, the sole C. elegans CRTC (CREB regulated transcriptional coactivator).
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
No sample metadata fields
View Samples