To test the "one-neuron-one-receptor" rule of olfactory receptor expression, we sequenced the transcriptomes of single olfactory sensory neurons from the main olfactory epithelium of adult (1 to 3 months) and newborn mice (postnatal day 4 to 10).
No associated publication
Sex, Specimen part, Cell line
View SamplesWe report the biological activity of a Py-Im polyamide targeted to the sequence 5'-WGWWCW-3', which is found in a subset of ARE half-sites. This molecule reduces the growth of enzalutamide-resistant LREX' cells, both in vitro and in vivo. Gene expression changes associated with polyamide treatment in both settings are deposited here.
No associated publication
Sex, Specimen part, Cell line
View SamplesVCaP cells were treated with 10uM of a Py-Im polyamided targeted to the DNA sequence 5''-WGWWCW-3'' for 24hrs. Gene expression changes are normalized to untreated VCaP cells.
No associated publication
Sex, Age, Specimen part, Cell line
View SamplesGene expression for shNT, shTRRAP-a, and shTRRAP-b expressing cells at ALI day 4 and day 14 was measured using RNA sequencing technology. Each experimental condition was performed in duplicate with two independent donors. Cells expressing the shRNA constructs (RFP+) were sorted by FACS, and the RNA was isolated and prepared for next generation sequencing analysis.
No associated publication
Sex, Specimen part, Disease, Treatment
View SamplesWe performed unbiased high-throughput RNA sequencing (mRNA-seq) of total RNA samples isolated from Tsc1-deficient livers in Cre- or Cre+ mice.
No associated publication
Sex, Specimen part, Disease, Cell line, Treatment
View SamplesTo study gene expression in liver regeneration, we subjected control mice to DDC (1,4-dihydro-2,4,6-trimethyl-pyridine-3,5-dicarboxylate ) diet for 16 days, isolated EpCam+ CD31-/CD45-/Ter119- cells using fluorescence-activated cell sorting and used these cells for single cell transcriptome analysis.
No associated publication
Sex, Specimen part, Cell line, Treatment
View SamplesEffect of ethanol or nicotine exposure on gene expression compared to control. Duplicate arrays from ethanol or nicotine treated animals compared with triplicate arrays from paired control animals. In total 4 treatment arrays (2 ethanol, 2 nicotine) and 3 control arrays (from control animals treated in parallel with ethanol-treated fish and nicotine-treated fish.)
Gene expression changes in a zebrafish model of drug dependency suggest conservation of neuro-adaptation pathways.
Specimen part, Compound
View SamplesNo description.
No associated publication
Sex, Specimen part, Cell line, Treatment
View SamplesStudy of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.
Specimen part, Cell line, Compound
View SamplesWe propose a microfluidic strategy to generate abundant brain organoids and further explore neurogenesis in fetal brain exposed to ethanol.
No associated publication
Sex, Specimen part, Disease, Cell line, Treatment
View Samples