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Rattus norvegicus
29 Downloadable Samples
Illumina HiSeq 2500
Description
Sacha inchi (Plukenetia volubilis L.) extract change the gut microbiota and alleviate the development of hypertension in spontaneously hypertensive rats
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples- Homo sapiens
- 2 Downloadable Samples
- Illumina HiSeq 4000
Description
Transcriptomic sequencing of human gastric cancer cell line (AGS) upon citral treatment
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line
View Samples
SRP136224- Danio rerio
- 12 Downloadable Samples
- IlluminaHiSeq2500
Description
To reveal the toxic mechanism of thifluzamide in zebrafish
Publication Title
No associated publication
Sample Metadata Fields
No sample metadata fields
View Samples SRP115073- Danio rerio
- 1 Downloadable Sample
- Illumina HiSeq 2500
Description
The study was to unravel the complex toxic effects of chemical contaminants on the health of organisms as based on different levels of biological profling.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Arabidopsis thaliana
- 9 Downloadable Samples
- Illumina HiSeq 2000
Description
The study aims to identify differences in gene expression in the root tissue of wild type Columbia-0 as well as Arabidopsis Mediator subunit mutants, med18 and med20 in response to the root pathogen Fusarium oxysporum. Roots were inoculated for 24 hours before harvesting for RNA isolation and paired end Illumina sequencing.
Publication Title
No associated publication
Sample Metadata Fields
Specimen part, Disease, Disease stage, Treatment
View Samples- Mus musculus
- 6 Downloadable Samples
Affymetrix Mouse Genome 430 2.0 Array (mouse4302)
Description
The aim of this study was to examine the role of indigenous lactobacilli in the physiological development of the stomach in mice using microarray analysis. In lactobacilli-associated gnotobiotic mice, an increased expression of the genes related to the muscle system development, such as nebulin and troponin, was observed. On the other hand, the expression of the gastrin gene dramatically decreased. A microarray analysis of the stomachs infected with H. pylori also showed both the up-regulation of muscle cell genes and the down-regulation of gastrin genes.
Publication Title
Role of indigenous lactobacilli in gastrin-mediated acid production in the mouse stomach.
Sample Metadata Fields
No sample metadata fields
View Samples- Homo sapiens
- 2 Downloadable Samples
- Illumina HiSeq 4000
Description
human Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptome
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part
View Samples- Drosophila melanogaster
- 2 Downloadable Samples
- Illumina HiSeq 4000
Description
This study revealed the EP impact on gene expression in fruit fly and provided new insight into the mechanisms of this response, which is helpful for understanding EP toxicity to humans.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples- Saccharomyces cerevisiae
- 4 Downloadable Samples
- Affymetrix Yeast Genome S98 Array (ygs98)
Description
The accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) causes stress and induces the unfolded protein response (UPR) which is characterised in part by the transcriptional induction of genes involved in assisting protein folding. Translational responses to ER stress have been less well described and here we report on a genome-wide analysis of translational regulation in the response to the ER stress-inducing agent dithiothreitol (DTT) in Saccharomyces cerevisiae. Although the observed polysome profiles were similar under control and ER stress conditions microarray analysis identified transcipt-specific translational regulation. Genes with functions in ribosomal biogenesis and assembly were translationally repressed under ER stress. In contrast mRNAs for known UPR genes, including the UPR transcription factor HAC1, the ER-oxidoreductase ERO1 and the ER-associated protein degradation (ERAD) gene DER1 were enriched in polysomal fractions under ER stress conditions. In addition, we show that splicing of HAC1 mRNA is required for efficient ribosomal loading and that Gcn2p is required for normal HAC1 splicing, so shedding light on the role of this protein kinase in the UPR pathway.
Publication Title
Transcript-specific translational regulation in the unfolded protein response of Saccharomyces cerevisiae.
Sample Metadata Fields
No sample metadata fields
View Samples- Gallus gallus
- 7 Downloadable Samples
- Illumina HiSeq 2000
Description
The goal of this study is to obtain the transcriptomes of chicken magnum in different natural developmental stages. There are totally five stages researched in this study and they are named D1, D2, D3, D4 and L. D1 to D4 are the abbreviations of developmental stage 1 to developmental stage 4 and L means laying stage. D1 refers to the lag phase (about 7 weeks old) in which the magnum has very slight change; D2 refers to the early proliferation phase (about 13 weeks old); D3 refers to the late proliferation phase (about 16 weeks old); D4 refers to the early differentiation phase (about 17 weeks old).
Publication Title
No associated publication
Sample Metadata Fields
Age
View Samples