the leaves of the downy mildew pre-inoculation and after 72 h of inoculation were sequenced for the high resistance varieties of soybean downy mildew - Jilin Xiaoji 1 and the high susceptible cultivar - Kefeng 1.The following results were obtained by transcriptome data analysis
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Specimen part
View SamplesNo description.
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Specimen part
View SamplesGene regulatory significance of the JmjC domain H235A point mutation in the yeast transcription factor Rph1, in log and post-diauxic shift (pds) phase
The histone demethylase activity of Rph1 affects telomeric silencing but is not required for nutrient signaling
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View SamplesRNA-seq was used to verify whether GPR31 is a high affinity receptor of 12-HETE. Normal human liver L02 cells, GPR31 knockout L02 cells and rescue of GPR31 knockout L02 cells under 12-HETE treatment simultaneously was used for RNA-seq.
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Sex, Specimen part, Cell line
View SamplesSingle-end RNA libraries were prepared from liver of Flox and IRF6-HKO mice with a high fat diet (HFD) for 10 weeks, and were sequenced using HiSeq 4000 in Beijing Genomics Institute. Three independent biological replicate samples were sequenced for each group.
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Sex, Age, Specimen part, Cell line
View SamplesThis study crossed Drosophila melanogaster genotypes from four populations to the reference genome line. RNAseq data was then generated to study natural variation in allele specific expression.
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Sex, Specimen part, Cell line
View SamplesT-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) share common morphologic and immunophenotypic features and are treated with similar therapeutic approaches. Nonetheless, they show distinct clinical presentations suggesting that they may represent two different biological entities. In order to investigate T-LBL and T-ALL biological characteristics we used transcriptional profiling approache. Genome-wide gene expression profiling, performed on 20 T-LBL and 10 T-ALL diagnostic specimens, showed that the two malignancies shared a large fraction of their transcriptional profile while a subset of genes appeared to be differentially expressed in T-LBL versus T-ALL. This gene signature included genes involved in chemotactic responses and angiogenesis which might play a role in the different tumor cell localization suggesting that T-LBL and T-ALL could be two distinct diseases with unique transcriptional characteristics.
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Specimen part, Disease
View SamplesIn order to identify genes dysregulated by the aberrant transcriptional activity of RUNX1-RUNX1T1, we used microarrays to determine the effect of this mutation on gene expression during myeloid and erythroid development of normal human progenitor cells.
Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia.
Specimen part
View SamplesSeven-day-old white-light-grown Arabidopsis seedlings were exposed for 15 minutes to polychromatic radiation with decreasing short-wave cut-off in the UV range, transferred back to the standard growth chamber and samples were taken 1 and 6 hours after the start of irradiation.
Genome-wide analysis of gene expression reveals function of the bZIP transcription factor HY5 in the UV-B response of Arabidopsis.
Age, Time
View SamplesGene expression profile in Calu-3 cells infected with MERS-CoV or SARS-CoV
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No sample metadata fields
View Samples