This study was designed to identify root specific transcriptome variation that occurs across genotypically diverse maize lines.
No associated publication
Age, Specimen part, Disease
View SamplesTranscriptome profiling is performed to reveal how Brassinosteroids (BRs) play a crucial role for plant vegetative growth and reproductive development.
No associated publication
Age, Specimen part
View SamplesThe aim of this experiment was to investigate the role of MIF during wound healing using BALB/C MIF null mice and in the context of reduced estrogen-associated impaired healing using ovariectomized mice (a mouse model of age-associated delayed healing). Ageing is associated with delayed cutaneous wound healing resulting from reduced estrogen levels. Macrophage migration inhibitory factor (MIF - NCBI RefSeq: NM_010798) is thought to mediate the effects of estrogen on wound healing. Gene expression was compared between wounds from ovariectomized MIF null mice and controls.
Macrophage migration inhibitory factor: a central regulator of wound healing.
Sex, Age, Specimen part, Subject
View SamplesIdentification and comparative analysis of differential gene expression in soybean leaf tissue under drought and flooding stress revealed by RNA-Seq
No associated publication
Age, Specimen part
View SamplesThe present study aimed to delineate the central mechanisms by which androgens delay wound repair. Blocking the conversion of testosterone to 5alpha-dihydrotestosterone (DHT) by 5alpha-reductase limits its ability to impair skin wound healing, suggesting that DHT is a more potent inhibitor of repair than is testosterone. This study aims to identify, through transcription profiling, potential mechanisms by which the 5alpha-reductase inhibitor MK-434 modulates repair. Microarray analysis of wound RNA samples from rats in which the transformation of testosterone to DHT is prevented has identified biological processes and key individual genes through which DHT may contribute to the altered healing profile in such animals. These include genes with putative roles in wound contraction and re-epithelialization.
5alpha-dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization.
Sex, Age, Specimen part, Compound
View SamplesThe aim of this experiment was measure the influence of age on cutaneous wound healing using human subjects. Increaded age has been associated with delayed wound healing in mouse models and in humans. Gene expression was compared between excisional biopsy wounds from young and old subjects.
Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly.
Sex, Age, Specimen part
View SamplesThe aim of this experiment was to understand secondary cell wall formation as it is a major constituent of wood and plant fibres. To identify potential novel genes involved in this process, data has been generated from Arabidopsis stem, leaf and hypocotyl tissue undergoing varying amounts of secondary cell wall synthesis.
Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics.
Age, Specimen part
View SamplesA study of diabetic neuropathy in dorsal root ganglia from streptozotocin-diabetic male wistar rats over the first 8 weeks of diabetes
Identification of changes in gene expression in dorsal root ganglia in diabetic neuropathy: correlation with functional deficits.
Sex, Age, Specimen part, Disease, Disease stage, Time
View SamplesWe compared gene expression profiles between asymptomatic and symptomatic atherosclerotic plaques from the same patient. This was accomplished by analyzing carotid plaques from four patients with bilateral high-grade carotid artery stenoses one being symptomatic (TIA or stroke) and the other asymptomatic.
Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques.
Sex, Age, Specimen part, Disease, Disease stage, Subject, Time
View SamplesCBX7-RIP-Seq data for HEK293T cells
No associated publication
Sex, Age, Specimen part, Cell line
View Samples