Hypoxia protects cancer cells from chemotherapeutic drug-induced cell death.
TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.
Cell line
View SamplesLipid rafts are cholesterol-rich cell signaling platforms and their physiological role can be explored by cholesterol depletion. To dress a global picture of transcriptional changes ongoing after lipid raft disruption, we performed whole-genome expression profiling in epidermal keratinocytes, a cell type which synthesizes its cholesterol in situ.
Transcriptional profiling after lipid raft disruption in keratinocytes identifies critical mediators of atopic dermatitis pathways.
Specimen part, Time
View Samples