Infectious bursal disease virus (IBDV) causes a highly contagious, immunosuppressive disease in chickens. The virus mainly infects immature B lymphocytes in the bursa of Fabricius (BF). Chicken B cell line DT40, an avian leukosis virus-induced B cell line, supports very virulent IBDV (vvIBDV) infection in vitro and thereby serves as a good model for investigating the infection and pathogenesis of this virus. However, a transcriptome-wide understanding of the interaction between vvIBDV and B cells has not yet been achieved. This study aimed to employ time-course DNA microarrays to investigate gene expression patterns in DT40 cells after infection with vvIBDV strain LX.
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Specimen part, Cell line, Time
View SamplesAims to find out differential expression genes (DEGs)in RAW264.7 cells during infection by Burkholderia pseudomallei infection
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Sex, Specimen part, Cell line, Treatment
View SamplesTo screening for gene expression differences between the ovaries of Baimei mutton with double-lambs and single-lamb using RNA-Seq method
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Sex, Specimen part
View SamplesDuring the pathogenesis of virus disease, lots of changes occur in plant hosts including the altered gene expression profiles. Rice stripe virus (RSV) is the type member of Tenuivirus, transmitted by Laodelphax striatellus in a circulative propagative man
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View SamplesSus scrofa has significant characteristics of high fecundity, roughage-resistance disease-resistance and cold-resistance,hence it is valuable to elucidate its transcriptome.
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Sex, Specimen part
View SamplesSeveral recombinat viruses of porcine circovirus type 2 (PCV2),including P1, P2, ZJ-R, VL258, and VL264, have been found. The PK15 cells were transfected by the molecular clones of the abovementioned viruses, where specific sets of genes are up-regulated or down-regulated.
Function analysis of proteins encoded by ORFs 1 to 8 of porcine circovirus-like virus P1 by microarray assay.
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View SamplesThe main objective of this study was to decipher the gene expression profile associated with the onset and early development of Wooden Breast Disease in commercial broiler chickens. To achieve this, pectoralis major muscle biopsy samples were harvested from high-breast-muscle-yield, purebred broiler line. The pectoral biopsy samples were collected from the cranial (week 2 and 3) and caudal (week 4) aspects of the muscle belly in birds which were allowed to grow up to 7 weeks of age. Three subsets of biopsy samples comprising 6 unaffected (U) and 10 affected (A) from week 2 and 4 and 4U and 12A from week 3 were processed for RNA-sequencing analysis. All selected samples were processed using Truseq stranded mRNA LT sample kit for paired-end 2x75-nucleotide sequencing with Illumina Hiseq 2500 sequencer.
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Sex, Age, Specimen part, Disease
View SamplesNo description.
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Sex, Age, Specimen part, Cell line, Treatment
View SamplesEmbryo implantation is an essential step for the establishment of pregnancy and is crucial for the successful embryo transplantation of in vitro fertilization embryos. The successful implantation of an embryo depends upon cellular and molecular dialog between the uterus and the embryo.
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Specimen part
View SamplesStaphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Cryptotanshinone, a natural plant product, has potent antimicrobial activity against S. aureus.
Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cryptotanshinone.
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