To elucidate the fundamental molecular mechanisms responsible for multistep hepatotumorigenesis, this study investigated genes that were upregulated in a stepwise manner from the nave liver condition through to chronic oxidative stress-induced hepatitis and liver tumor by time-series microarray analysis. The time-dependent gene expression profile should reflect the multistep process of hepatotumorigenesis, and might identify genes that function specifically in hepatotumorigenesis.
IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress.
Sex, Age, Specimen part, Disease
View SamplesWe used microarrays to identified new factor that regulates cancer stem cell population in shRNA DYRK2 cells using stable DYRK2 knockdown cells and mammosphere.
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Specimen part
View SamplesWe found that norgestimate effectively inhibits staphylococcal biofilm formation.
No associated publication
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View SamplesWe demonstrated that, four weeks after the pulmonary artery banding (PAB) operation, rats could be divided into two groups: an F+ group in which the fibrotic area occupied more than 6.5% of the whole area of the heart tissues, and an F- group in which the fibrotic area occupied less than 6.5% of this area.
Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1.
Sex, Specimen part
View Sampleswe aimed to explore the potential therapeutic effects of human mesenchymal stem cell on severe liver disease
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Sex, Specimen part, Cell line
View SamplesAnalyze of RNA expression of Old Fibroblast and Young Fibroblast. Compare RNA expression of Old Fibroblast to RNA expression of Young Fbroblast
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Sex, Specimen part
View Sampleswe analysis of sham fibroblast and UVA fibroblast RNA expression using RNA sequencing and compare RNA expression.
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Sex, Specimen part
View SamplesWe generate miR-25 KO mice by Cas-9 technology, and run 5 month kidney RNA sequencing.
No associated publication
Sex, Specimen part, Cell line
View SamplesAdult neural stem cells derived from wild type and Sirt1 conditional knockout mice were treated with or without X-ray, the total RNA extracted from these cells were used for RNA sequencing.
No associated publication
Sex, Age, Specimen part, Cell line
View SamplesNo description.
No associated publication
Sex, Age, Specimen part
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