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accession-icon E-MEXP-254
Plasmodiophora brassicae infection of Arabidopsis thaliana
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Arabipdosis thaliana (ecotype Col-0) was infected with the root pathogen Plasmodiophora brassicae. Gene expression of the host plant has been analyzed at two time points after inoculation (10 and 23 days after inoculation) compared to the correspondend control plants.

Publication Title

Transcriptome analysis of Arabidopsis clubroots indicate a key role for cytokinins in disease development.

Sample Metadata Fields

Age, Specimen part, Cell line, Time

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accession-icon GSE18624
H2A.Z - Containing Nucleosomes Mediate the Thermosensory Response in Arabidopsis
  • organism-icon Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

We isolated mutants in Arabidopsis with enhanced ambient temperature response. Microarray analysis was performed to understand the extent to which ambient temperature transcriptome is perturbed in the mutants in comparison with the WT at non inductive 12 C and after shift to inductive 27 C for 2 h and 24 h.

Publication Title

H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis.

Sample Metadata Fields

Specimen part

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accession-icon E-MTAB-2297
pft1 glucose responses
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Determining the role of the Mediator subunit MED25/PFT1 in coordinating the expression of glucose responsive genes in Arabidopsis thaliana

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Time

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accession-icon GSE19785
Expression data from Arabidopsis and Maize leaves
  • organism-icon Zea mays, Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Many animal and plant species exhibit increased growth rates, reach larger sizes and, in the cases of crops and farm animals, produce higher yields when bred as hybrids between genetically differing strains, a phenomenon known as hybrid vigour or heterosis. Despite the importance of heterosis, and its extensive genetic analysis, there has been little understanding of its molecular basis. We aimed to determine whether characteristics of the leaf transcriptome, as an indicator of the innate functional genetic architecture of a plant line, could be used as markers to predict heterosis and the performance of hybrids, a methodology we term Association Transcriptomics. Relationships between transcript abundance of specific genes and the values of heterosis and heterosis-dependent traits were identified and mathematical models were constructed that relate gene expression characteristics in inbred lines of Arabidopsis thaliana and maize with vegetative biomass and for grain yield, respectively, in corresponding hybrids.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE9201
Identification of genes responding to the activity of the Arabidopsis cytochrome P450 KLUH/CYP78A5
  • organism-icon Arabidopsis thaliana
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The Arabidopsis cytochrome P450 KLUH (KLU)/CYP78A5 promotes organ growth in a non-cell autonomous manner. To identify genes regulated by KLU activity, homozygous klu-2 mutants carrying constructs for EtOH-inducible overexpression of wild-type KLU (35S::AlcR-AlcA::KLU) or of enzymatically inactive KLU protein (35S::AlcR-AlcA::KLUmut) were induced with EtOH and sampled at 90 min and 240 min after induction for gene expression changes.

Publication Title

Control of plant organ size by KLUH/CYP78A5-dependent intercellular signaling.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE80070
Whole transcript expression profiling of short-term and long-term hypoxic neural stem cells (NSCs)
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

Transcriptome analysis of murine foetal NSCs (E14) after short-term (48 hours) and long-term (13 days) hypoxic (3% oxygen) culture compared to normoxic culture (21% oxygen)

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE36687
Microarray of Rnaseh2b KOF and RnaseH2b wild type fetal liver
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Fetal liver of E14.5 RNaseh2b KOF and Rnaseh2b wild type embryos was isolated, RNA was extracted and microarray analysis using Affymetrix Mouse 430 2.0 gene chip was performed

Publication Title

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity.

Sample Metadata Fields

Specimen part

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accession-icon GSE49680
Expression analysis of LM8 osteosarcoma cells overexpressing human Prolyl Hydroxylase Domain Protein-4 (PHD4) and LM8 control cells
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Expression 430A Array (moe430a)

Description

PHD4 regulates the expression of Hypxia-inducible Factor 2 (HIF-2) alpha in LM8 osteosarcoma cells. PHD4 overexpression inhibits the growth of experimental tumor in syngenic mice but stimulates angiogenesis via Transforming Growth-Factor (TGF)-alpha.

Publication Title

PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α.

Sample Metadata Fields

Cell line, Treatment

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accession-icon SRP132246
RNA- Seq analysis of soybean varieties during early stages of charcoal rot infection
  • organism-icon Glycine max
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The RNA-Seq analysis of charcoal rot infection in two soybean genotypes during the initial infection. The study would provide insights into the genetic re-programming of transcriptome, following infection.

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Disease, Treatment

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accession-icon SRP065617
Zea mays cultivar:Z59 Transcriptome or Gene expression
  • organism-icon Zea mays
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500, NextSeq 500

Description

RNA-Seq analysis of the drought responsive transcriptome of Zea mays cultivar Z59

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Treatment

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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