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accession-icon GSE68950
caArray_golub-00327: Sanger cell line Affymetrix gene expression project
  • organism-icon Homo sapiens
  • sample-icon 744 Downloadable Samples
  • Technology Badge Icon Affymetrix HT Human Genome U133A Array (hthgu133a)

Description

The microarray gene expression pattern was studied using 798 different cancer cell lines. The cancer cell lines are obtained from different centers. Annotation information were provided in the supplementary file.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE83130
caArray_meyer-00180: TCGA GBM: Analysis of Gene Expression for Glioblastoma Multiforme Using Affymetrix HT_HG-U133A (Broad)
  • organism-icon Homo sapiens
  • sample-icon 696 Downloadable Samples
  • Technology Badge Icon Affymetrix HT Human Genome U133A Array (hthgu133a)

Description

TCGA Analysis of RNA Expression for Glioblastoma Multiforme Using Affymetrix HT_HG-U133A

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage, Subject

View Samples
accession-icon GSE68848
caArray_fine-00037: Rembrandt_GeneExpression
  • organism-icon Homo sapiens
  • sample-icon 577 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This is Rembrandt gene expression data (Affymetrix HG-U133Plus2).

Publication Title

Rembrandt: helping personalized medicine become a reality through integrative translational research.

Sample Metadata Fields

Specimen part, Disease, Disease stage

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accession-icon GSE82191
caArray_meyer-00114: TCGA Analysis of Gene Expression for Ovarian Serous Cystadenocarcinoma Using Affymetrix HT_HG-U133A
  • organism-icon Homo sapiens
  • sample-icon 527 Downloadable Samples
  • Technology Badge Icon Affymetrix HT Human Genome U133A Array (hthgu133a)

Description

TCGA Analysis of RNA Expression for Ovarian Serous Cystadenocarcinoma Using Affymetrix HT_HG-U133A

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease stage, Subject

View Samples
accession-icon GSE68661
caArray_EXP-485: TCGA Analysis of Gene Expression for Ovarian Serous Cystadenocarcinoma Using Affymetrix HT_HG-U133A
  • organism-icon Homo sapiens
  • sample-icon 525 Downloadable Samples
  • Technology Badge Icon Affymetrix HT Human Genome U133A Array (hthgu133a)

Description

TCGA Analysis of RNA Expression for Glioblastoma Multiforme Using Affymetrix HT_HG-U133A

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease stage, Subject

View Samples
accession-icon GSE83232
caArray_mille-00271: Uppsala cohort
  • organism-icon Homo sapiens
  • sample-icon 516 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

breast cancer

Publication Title

No associated publication

Sample Metadata Fields

Disease

View Samples
accession-icon GSE68555
caArray_becic-00235: Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy
  • organism-icon Homo sapiens
  • sample-icon 444 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U95A Array (hgu95a)

Description

The incidence of prostate cancer is frequent, occurring in almost one-third of men older than 45 years. Only a fraction of the cases reach the stages displaying clinical significance. Despite the advances in our understanding of prostate carcinogenesis and disease progression, our knowledge of this disease is still fragmented. Identification of the genes and patterns of gene expression will provide a more cohesive picture of prostate cancer biology. PATIENTS AND METHODS: In this study, we performed a comprehensive gene expression analysis on 152 human samples including prostate cancer tissues, prostate tissues adjacent to tumor, and organ donor prostate tissues, obtained from men of various ages, using the Affymetrix (Santa Clara, CA) U95a, U95b, and U95c chip sets (37,777 genes and expression sequence tags). RESULTS: Our results confirm an alteration of gene expression in prostate cancer when comparing with nontumor adjacent prostate tissues. However, our study also indicates that the gene expression pattern in tissues adjacent to cancer is so substantially altered that it resembles a cancer field effect. CONCLUSION: We also found that gene expression patterns can be used to predict the aggressiveness of prostate cancer using a novel model.

Publication Title

Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage

View Samples
accession-icon GSE68790
caArray_EXP-578: Gene Expression Profiles of Pediatric B-Precursor High-Risk Acute Lymphoblastic Leukemia (COG Study AALL0232 - Cohort 1).
  • organism-icon Homo sapiens
  • sample-icon 274 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This experiment comprises 283 CEL files generated on the Affymetrix U133 Plus 2.0 gene expression microarray platform, using patient peripheral blood and bone marrow samples from the first cohort of patients accrued to Children's Oncology Group Study AALL0232. No clinical covariate data is provided at this time as the clinical study is not yet published. Researchers who would like to request outcome or other covariate data are asked to contact Dr. Cheryl Willman, cwillman@unm.edu, 505.272.5622 (University of New Mexico) and Dr. Steven Hunger, Stephen.Hunger@childrenscolorado.org (Children's Oncology Group and Children's Hospital Colorado) to arrange a collaboration.

Publication Title

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project.

Sample Metadata Fields

Disease

View Samples
accession-icon GSE92708
caArray_willm-00090: Gene Expression Profiling Reveals Novel Genes for Improved Risk Classification and Outcome Prediction in Pediatric Acute Lymphoblastic Leukemia: Identification, Cloning, and Validation of OPAL1
  • organism-icon Homo sapiens
  • sample-icon 252 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U95 Version 2 Array (hgu95av2)

Description

Affymetrix HG_U95Av2 oligonucleotide microarrays were used to perform gene expression profiling of 254 cases of pediatric ALL in order to determine genes predictive of outcome that may be useful in refining risk classification.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage

View Samples
accession-icon GSE83227
caArray_meyer-00191: Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
  • organism-icon Homo sapiens
  • sample-icon 254 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U95 Version 2 Array (hgu95av2)

Description

We have generated a molecular taxonomy of lung carcinoma, the leading cause of cancer death in the United States and worldwide. Using oligonucleotide microarrays, we analyzed mRNA expression levels corresponding to 12,600 transcript sequences in 186 lung tumor samples, including 139 adenocarcinomas resected from the lung. Hierarchical and probabilistic clustering of expression data defined distinct subclasses of lung adenocarcinoma. Among these were tumors with high relative expression of neuroendocrine genes and of type II pneumocyte genes, respectively. Retrospective analysis revealed a less favorable outcome for the adenocarcinomas with neuroendocrine gene expression. The diagnostic potential of expression profiling is emphasized by its ability to discriminate primary lung adenocarcinomas from metastases of extra-pulmonary origin. These results suggest that integration of expression profile data with clinical parameters could aid in diagnosis of lung cancer patients.

Publication Title

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses.

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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