A series contains a set of transcript intensity values measured by Affymetrix microarray.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
Sex, Specimen part
View SamplesThis series of microarray data contain transcript intensity of mpkCCD cells.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
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View SamplesVasopressin is the major hormone that regulates renal water excretion. It does so by binding to a receptor in renal collecting duct cells, triggering signaling pathways that ultimately regulate the abundance, location, and activity of the water channel protein aquaporin 2. We took an advantage of quantitative large scale proteomic technologies and oligonucleotide microarrays to quantify steady state changes in protein and transcript abundances in response to vasopressin in a collecting duct cell line, mpkCCD clone 11 (Yu et al. PNAS 2009, 106:2441-2446). This cell line originally developed by Alan Vandewalles group recapitulates vasopressin-mediated AQP2 expression and phosphorylation as seen in native colleting duct cells.
No associated publication
Specimen part, Cell line
View SamplesAnalysis of gene expression profiles in MEF cell lines in the absence or presence of STAT3 following IFNa stimulation. This study is to unveil possible role of STAT3 during type I IFN-mediated gene induction and functions.
STAT3 negatively regulates type I IFN-mediated antiviral response.
Cell line
View SamplesFreshly isolated rat kidney proximal tubules were subjected for transcript profiling.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
Sex, Specimen part
View SamplesFreshly isolated rat kidney medullary thick ascending limbs were subjected for transcript profiling.
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.
Sex, Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Integrated analyses of copy number variations and gene expression in lung adenocarcinoma.
Sex, Age, Specimen part
View SamplesAlthough smoking is the major risk factor for lung cancer, only 7% of female lung cancer patients in Taiwan have a history of cigarette smoking, extremely lower than those in Caucasian females. This report is a comprehensive analysis of the molecular signature of non-smoking female lung cancer in Taiwan.
Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women.
Sex, Age, Specimen part
View SamplesAccumulation of negative stressful life events caused major depressive disorder (MDD) a major public health problem related to disability around the world. For effective therapy and disease managements, a comprehensive genomic analysis to identify objective signatures is required to grasp pathophysiological changes and applicable markers.
No associated publication
Sex, Specimen part
View SamplesEpithelial appendages are the product of epithelial mesenchymal interactions. Tissue recombination experiments showed that in general, the dermis determines the phenotype of the epithelial appendage. Chicken dorsal skin epithelium interacts with its underlying mesenchyme to form feathers beginning at E7 (H&H stage 31), while metatarsal scale epithelium interacts with its mesenchyme to form scales beginning at E9 (H&H stage 35) which stabilize around E12 (H&H stage 38).
Emergence of differentially regulated pathways associated with the development of regional specificity in chicken skin.
Specimen part
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