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accession-icon GSE13672
Mouse mpkCCD cells, Rat Kidney Proximal Tubule, and Rat Kidney Medullary Thick Ascending Limb
  • organism-icon Mus musculus, Rattus norvegicus
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

A series contains a set of transcript intensity values measured by Affymetrix microarray.

Publication Title

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE13667
mpkCCD_Cell_Clones
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This series of microarray data contain transcript intensity of mpkCCD cells.

Publication Title

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE19938
Expression data from mouse collecting duct cell, mpkCCD, in response to a peptide hormone vasopressin analog, dDAVP
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Vasopressin is the major hormone that regulates renal water excretion. It does so by binding to a receptor in renal collecting duct cells, triggering signaling pathways that ultimately regulate the abundance, location, and activity of the water channel protein aquaporin 2. We took an advantage of quantitative large scale proteomic technologies and oligonucleotide microarrays to quantify steady state changes in protein and transcript abundances in response to vasopressin in a collecting duct cell line, mpkCCD clone 11 (Yu et al. PNAS 2009, 106:2441-2446). This cell line originally developed by Alan Vandewalles group recapitulates vasopressin-mediated AQP2 expression and phosphorylation as seen in native colleting duct cells.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE25044
Genome-wide analysis of IFNa response in WT and STAT3KO MEFs
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina mouse-6 v1.1 expression beadchip

Description

Analysis of gene expression profiles in MEF cell lines in the absence or presence of STAT3 following IFNa stimulation. This study is to unveil possible role of STAT3 during type I IFN-mediated gene induction and functions.

Publication Title

STAT3 negatively regulates type I IFN-mediated antiviral response.

Sample Metadata Fields

Cell line

View Samples
accession-icon GSE13668
Profiling of Transcripts in Rat Proximal Tubule
  • organism-icon Rattus norvegicus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Freshly isolated rat kidney proximal tubules were subjected for transcript profiling.

Publication Title

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE13669
Profiling of Transcripts in Rat Kidney Medullary Thick Ascending Limb
  • organism-icon Rattus norvegicus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Freshly isolated rat kidney medullary thick ascending limbs were subjected for transcript profiling.

Publication Title

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE33356
Genome-wide screening of genomic alterations and transcriptional modulation in non-smoking female lung cancer in Taiwan
  • organism-icon Homo sapiens
  • sample-icon 114 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Integrated analyses of copy number variations and gene expression in lung adenocarcinoma.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE19804
Genome-wide screening of transcriptional modulation in non-smoking female lung cancer in Taiwan
  • organism-icon Homo sapiens
  • sample-icon 114 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Although smoking is the major risk factor for lung cancer, only 7% of female lung cancer patients in Taiwan have a history of cigarette smoking, extremely lower than those in Caucasian females. This report is a comprehensive analysis of the molecular signature of non-smoking female lung cancer in Taiwan.

Publication Title

Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE151807
Expression data from brain parts (amygdala, hippocampus, prefrontal cortex, and cerebral cortex) from mice with or without chronic mild stress (CMS) treatments.
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Accumulation of negative stressful life events caused major depressive disorder (MDD) a major public health problem related to disability around the world. For effective therapy and disease managements, a comprehensive genomic analysis to identify objective signatures is required to grasp pathophysiological changes and applicable markers.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE62882
Expression data from embryonic chicken feather and scale skins
  • organism-icon Gallus gallus
  • sample-icon 19 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Epithelial appendages are the product of epithelial mesenchymal interactions. Tissue recombination experiments showed that in general, the dermis determines the phenotype of the epithelial appendage. Chicken dorsal skin epithelium interacts with its underlying mesenchyme to form feathers beginning at E7 (H&H stage 31), while metatarsal scale epithelium interacts with its mesenchyme to form scales beginning at E9 (H&H stage 35) which stabilize around E12 (H&H stage 38).

Publication Title

Emergence of differentially regulated pathways associated with the development of regional specificity in chicken skin.

Sample Metadata Fields

Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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